# OnCo record pegylated-liposomal-doxorubicin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/pegylated-liposomal-doxorubicin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "pegylated-liposomal-doxorubicin" ;
  schema:name "Pegylated liposomal doxorubicin"@en ;
  schema:description "Doxorubicin wrapped in a fatty bubble so it reaches tumours with less heart damage; a workhorse of relapsed ovarian cancer."@en ;
  schema:url <https://onco.cc/drugs/pegylated-liposomal-doxorubicin/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Liposomal_doxorubicin> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Pegylated%20liposomal%20doxorubicin>, <https://doi.org/10.1016/j.jconrel.2012.03.020> ;
  onco:status "approved" ;
  onco:modality "Cytotoxic (liposomal anthracycline)" ;
  schema:alternateName "Doxil / Caelyx" ;
  onco:approval "US 1995: AIDS-related Kaposi sarcoma after prior chemotherapy (Doxil, NDA 050718)", "US 1999: Ovarian cancer refractory to platinum and paclitaxel" ;
  onco:acceleratedApproval "US 1995-11-17: Kaposi's sarcoma in AIDS patients with disease progression on prior combination chemotherapy or who are intolerant to such therapy", "US 1999-06-28: Metastatic ovarian carcinoma refractory to paclitaxel and platinum-based chemotherapy" ;
  onco:acceleratedApprovalConfirmed "US 2005-01-28: Metastatic ovarian carcinoma refractory to paclitaxel and platinum-based chemotherapy", "US 2008-06-10: Kaposi's sarcoma in AIDS patients with disease progression on prior combination chemotherapy or who are intolerant to such therapy" ;
  onco:cancers <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/multiple-myeloma/>, <https://onco.cc/cancers/sarcoma/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/topoisomerase-inhibitors/> ;
  onco:companies <https://onco.cc/companies/cspc/> ;
  onco:institutions <https://onco.cc/institutions/hebrew-university-of-jerusalem/> ;
  onco:trials <https://onco.cc/trials/nct06072781/>, <https://onco.cc/trials/nct07604766/>, <https://onco.cc/trials/nct06619236/>, <https://onco.cc/trials/nct06014528/>, <https://onco.cc/trials/actuate-1801/>, <https://onco.cc/trials/nct04274426/>, <https://onco.cc/trials/nct07286266/>, <https://onco.cc/trials/nct07109414/> ;
  onco:people <https://onco.cc/people/yechezkel-barenholz/>, <https://onco.cc/people/alberto-gabizon/> .