# OnCo record pemetrexed (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/pemetrexed/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "pemetrexed" ;
  schema:name "Pemetrexed"@en ;
  schema:description "Pemetrexed is the chemotherapy that, with a platinum drug, became the first approved treatment for mesothelioma in 2004, and is still the backbone today."@en ;
  schema:url <https://onco.cc/drugs/pemetrexed/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Pemetrexed> ;
  owl:sameAs <http://www.wikidata.org/entity/Q415220> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Pemetrexed> ;
  onco:status "approved" ;
  onco:modality "Cytotoxic (antifolate)" ;
  schema:alternateName "Alimta (and generics)" ;
  onco:approval "US 2004: Unresectable pleural mesothelioma with cisplatin", "US 2008: Non-squamous NSCLC first line" ;
  onco:acceleratedApproval "US 2004-08-19: As a single agent for locally advanced or metastatic NSCLC after prior chemotherapy", "US 2008-09-26: Non-squamous NSCLC: 1) as initial treatment with cisplatin; 2) as a single agent after prior chemotherapy", "US 2018-06-04: In combination with pembrolizumab and carboplatin for first-line treatment of metastatic non-squamous NSCLC" ;
  onco:acceleratedApprovalConfirmed "US 2009-07-02: As a single agent for locally advanced or metastatic NSCLC after prior chemotherapy", "US 2009-07-02: Non-squamous NSCLC: 1) as initial treatment with cisplatin; 2) as a single agent after prior chemotherapy", "US 2019-01-30: In combination with pembrolizumab and carboplatin for first-line treatment of metastatic non-squamous NSCLC" ;
  onco:cancers <https://onco.cc/cancers/mesothelioma/>, <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:companies <https://onco.cc/companies/eli-lilly/> ;
  onco:trials <https://onco.cc/trials/keynote-483/>, <https://onco.cc/trials/maps/>, <https://onco.cc/trials/checkmate-743/>, <https://onco.cc/trials/gefitinib-chemo-tmh/>, <https://onco.cc/trials/nct06212752/>, <https://onco.cc/trials/nct04351555/>, <https://onco.cc/trials/nct06305754/>, <https://onco.cc/trials/nct06899126/>, <https://onco.cc/trials/nct04379635/>, <https://onco.cc/trials/nct05800015/>, <https://onco.cc/trials/nct06956001/>, <https://onco.cc/trials/nct06564844/>, <https://onco.cc/trials/nct06417814/>, <https://onco.cc/trials/nct06459180/>, <https://onco.cc/trials/nct06452277/>, <https://onco.cc/trials/nct05116462/>, <https://onco.cc/trials/nct03800134/>, <https://onco.cc/trials/nct06711900/>, <https://onco.cc/trials/nct06396065/>, <https://onco.cc/trials/nct04129502/>, <https://onco.cc/trials/nct06712316/>, <https://onco.cc/trials/nct06312137/>, <https://onco.cc/trials/nct05555732/>, <https://onco.cc/trials/nct05870319/>, <https://onco.cc/trials/nct06726265/>, <https://onco.cc/trials/nct06561386/>, <https://onco.cc/trials/nct02486718/>, <https://onco.cc/trials/nct05722015/>, <https://onco.cc/trials/nct07642024/>, <https://onco.cc/trials/nct06793215/>, <https://onco.cc/trials/nct06687369/>, <https://onco.cc/trials/nct06074588/>, <https://onco.cc/trials/nct05048797/>, <https://onco.cc/trials/nct06627647/>, <https://onco.cc/trials/nct04956692/>, <https://onco.cc/trials/nct05984277/>, <https://onco.cc/trials/nct03178552/>, <https://onco.cc/trials/nct07777822/>, <https://onco.cc/trials/nct07178795/>, <https://onco.cc/trials/nct06097728/>, <https://onco.cc/trials/nct07100080/>, <https://onco.cc/trials/nct05668988/>, <https://onco.cc/trials/nct06382116/>, <https://onco.cc/trials/nct05180799/>, <https://onco.cc/trials/nct06475300/>, <https://onco.cc/trials/nct03970746/>, <https://onco.cc/trials/nct06514027/>, <https://onco.cc/trials/nct06448754/>, <https://onco.cc/trials/nct06946797/>, <https://onco.cc/trials/nct05633667/>, <https://onco.cc/trials/nct07680764/>, <https://onco.cc/trials/nct06731907/>, <https://onco.cc/trials/nct05789082/>, <https://onco.cc/trials/nct05904379/>, <https://onco.cc/trials/nct03775486/>, <https://onco.cc/trials/nct06943820/>, <https://onco.cc/trials/nct05431270/>, <https://onco.cc/trials/nct05635708/>, <https://onco.cc/trials/nct06996782/>, <https://onco.cc/trials/nct06706076/>, <https://onco.cc/trials/nct06161441/>, <https://onco.cc/trials/nct05098132/>, <https://onco.cc/trials/nct06162221/>, <https://onco.cc/trials/nct04736173/>, <https://onco.cc/trials/nct07122687/>, <https://onco.cc/trials/nct07070440/>, <https://onco.cc/trials/nct07020221/>, <https://onco.cc/trials/nct04665206/>, <https://onco.cc/trials/nct05841472/>, <https://onco.cc/trials/nct06758557/>, <https://onco.cc/trials/nct05403385/>, <https://onco.cc/trials/nct04198766/>, <https://onco.cc/trials/nct05742607/>, <https://onco.cc/trials/nct04956640/>, <https://onco.cc/trials/nct07486817/>, <https://onco.cc/trials/nct05609578/>, <https://onco.cc/trials/nct06623422/>, <https://onco.cc/trials/nct05498428/>, <https://onco.cc/trials/nct06246110/>, <https://onco.cc/trials/nct06667076/>, <https://onco.cc/trials/nct06474455/>, <https://onco.cc/trials/nct07415031/>, <https://onco.cc/trials/nct06783647/>, <https://onco.cc/trials/nct06008093/>, <https://onco.cc/trials/nct04538664/>, <https://onco.cc/trials/nct05687266/>, <https://onco.cc/trials/nct06151574/>, <https://onco.cc/trials/nct07586202/>, <https://onco.cc/trials/nct04025879/>, <https://onco.cc/trials/nct05261399/>, <https://onco.cc/trials/nct06119581/>, <https://onco.cc/trials/nct07492680/>, <https://onco.cc/trials/nct07171606/>, <https://onco.cc/trials/nct05112965/>, <https://onco.cc/trials/nct06385678/>, <https://onco.cc/trials/nct06194448/>, <https://onco.cc/trials/nct07109531/>, <https://onco.cc/trials/nct05456256/>, <https://onco.cc/trials/nct06772623/>, <https://onco.cc/trials/nct03003962/>, <https://onco.cc/trials/nct06875310/>, <https://onco.cc/trials/nct05410145/>, <https://onco.cc/trials/nct04988295/>, <https://onco.cc/trials/nct06788912/>, <https://onco.cc/trials/nct05443126/>, <https://onco.cc/trials/nct06970639/>, <https://onco.cc/trials/nct06741644/>, <https://onco.cc/trials/nct04380636/> .