# OnCo record penelope-b (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/penelope-b/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "penelope-b", "NCT01864746" ;
  schema:name "PENELOPE-B"@en ;
  schema:description "PENELOPE-B tested whether a year of the CDK4/6 inhibitor palbociclib after chemotherapy and surgery would prevent recurrence in women at high risk; it did not, one of two trials to show that palbociclib does not work in early breast cancer even though later drugs in the class do."@en ;
  schema:url <https://onco.cc/trials/penelope-b/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01864746> ;
  onco:status "negative" ;
  onco:tag "subtype-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/hr-positive-early-high-risk/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:drugs <https://onco.cc/drugs/palbociclib/> ;
  onco:companies <https://onco.cc/companies/pfizer/> ;
  onco:people <https://onco.cc/people/sibylle-loibl/> .