# OnCo record pentostatin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/pentostatin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "pentostatin" ;
  schema:name "Pentostatin"@en ;
  schema:alternateName "Deoxycoformycin"@en, "2'-deoxycoformycin"@en, "Nipent" ;
  schema:description "An intravenous drug given every other week that produces long remissions in hairy cell leukaemia by poisoning the leukaemic lymphocytes' purine metabolism; cladribine is the one-week alternative."@en ;
  schema:url <https://onco.cc/drugs/pentostatin/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Pentostatin> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=pentostatin>, <https://doi.org/10.1200/JCO.1995.13.4.974> ;
  onco:status "approved" ;
  onco:tag "gap-fill", "generic" ;
  onco:modality "Purine analogue, adenosine deaminase inhibitor" ;
  onco:approval "US 1991: Hairy cell leukaemia (initially alpha-interferon-refractory; later untreated disease)" ;
  onco:related <https://onco.cc/drugs/cladribine/> ;
  onco:cancers <https://onco.cc/cancers/hairy-cell-leukemia/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/ada/> ;
  onco:trials <https://onco.cc/trials/nct00254163/>, <https://onco.cc/trials/nct01188798/>, <https://onco.cc/trials/nct01059786/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-grever-j-clin-oncol/> .