# OnCo record persevera (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/persevera/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "persevera", "NCT04546009" ;
  schema:name "persevERA"@en ;
  schema:description "An oral SERD did not beat the aromatase inhibitor in first-line treatment when both were combined with palbociclib. Oral SERDs earn their place after resistance, not before it."@en ;
  schema:url <https://onco.cc/trials/persevera/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04546009> ;
  onco:status "negative" ;
  onco:tag "failure", "lesson:selection" ;
  onco:phase "3" ;
  schema:startDate "2020-10-09" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/endocrine-therapy/> ;
  onco:drugs <https://onco.cc/drugs/giredestrant/>, <https://onco.cc/drugs/palbociclib/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> .