# OnCo record pexidartinib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/pexidartinib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "pexidartinib" ;
  schema:name "Pexidartinib"@en ;
  schema:description "Pexidartinib is the first drug for tenosynovial giant cell tumour, a benign but destructive joint tumour; it is effective but has liver toxicity that requires a restricted programme."@en ;
  schema:url <https://onco.cc/drugs/pexidartinib/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Pexidartinib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q25100640> ;
  schema:citation <https://doi.org/10.1016/S0140-6736(19)30764-0>, <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=pexidartinib> ;
  onco:status "approved" ;
  onco:tag "gap-fill" ;
  onco:modality "Small-molecule CSF1R/KIT/FLT3 inhibitor" ;
  schema:alternateName "Turalio" ;
  onco:approval "US 2019: Symptomatic tenosynovial giant cell tumour not amenable to surgery" ;
  onco:cancers <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/tenosynovial-giant-cell-tumour/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/csf1r/>, <https://onco.cc/targets/kit/> ;
  onco:companies <https://onco.cc/companies/daiichi-sankyo/> ;
  onco:trials <https://onco.cc/trials/nct04488822/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tap-lancet/> .