# OnCo record pgr (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/pgr/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "pgr" ;
  schema:name "Progesterone receptor (PGR)"@en ;
  schema:description "The progesterone receptor is the hormone receptor that, alongside the oestrogen receptor, marks breast cancers likely to respond to hormone therapy, and it is the target of the progestins megestrol and medroxyprogesterone used in endometrial and breast cancer."@en ;
  schema:url <https://onco.cc/targets/pgr/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Progesterone_receptor>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:8910>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000082175>, <https://www.uniprot.org/uniprotkb/P06401/entry>, <https://www.ncbi.nlm.nih.gov/gene/5241> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P06401/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:8910> ;
  schema:alternateName "PGR" ;
  onco:targetClass "nuclear-receptor" ;
  onco:firstDescribed "1987"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/estrogen-receptor/>, <https://onco.cc/biomarkers/pr-status/> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/endometrial/> ;
  onco:drugs <https://onco.cc/drugs/megestrol/>, <https://onco.cc/drugs/megestrol-progestins/> ;
  onco:terms <https://onco.cc/terms/ihc/> .
