# OnCo record phlpp2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/phlpp2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "phlpp2" ;
  schema:name "PHLPP2"@en ;
  schema:alternateName "PH domain and leucine rich repeat protein phosphatase 2"@en, "PHLPPL"@en, "PPM3B"@en, "PHLPP2" ;
  schema:description "PHLPP2 is a phosphatase that switches AKT off; it is lost in most colorectal cancers, which leaves the survival pathway on."@en ;
  schema:url <https://onco.cc/targets/phlpp2/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:29149>, <https://www.uniprot.org/uniprotkb/Q6ZVD8/entry> ;
  onco:tag "cansim-terms" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:29149>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000040199>, <https://www.uniprot.org/uniprotkb/Q6ZVD8/entry>, <https://www.ncbi.nlm.nih.gov/gene/23035> ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:pathways <https://onco.cc/pathways/pi3k-akt-mtor/> ;
  onco:terms <https://onco.cc/terms/co-amplification/>, <https://onco.cc/terms/cancer-ai-vocabulary/>, <https://onco.cc/terms/pathway-activation-state/>, <https://onco.cc/terms/mrna-protein-concordance/> .