# OnCo record pi3k-akt-mtor-inhibitors (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/pi3k-akt-mtor-inhibitors/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "pi3k-akt-mtor-inhibitors" ;
  schema:name "PI3K, AKT and mTOR inhibitors"@en ;
  schema:description "Drugs against one of the most commonly mutated growth pathways in cancer, now used with hormone therapy in breast cancer and in kidney and neuroendocrine tumours, with high blood sugar as the shared side effect."@en ;
  schema:url <https://onco.cc/technologies/pi3k-akt-mtor-inhibitors/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/PI3K/AKT/mTOR_pathway> ;
  schema:citation <https://en.wikipedia.org/wiki/PI3K/AKT/mTOR_pathway> ;
  onco:status "approved" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/rcc/> ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/> ;
  onco:targets <https://onco.cc/targets/pik3ca/>, <https://onco.cc/targets/akt/>, <https://onco.cc/targets/mtor/> ;
  onco:drugs <https://onco.cc/drugs/everolimus/>, <https://onco.cc/drugs/temsirolimus/>, <https://onco.cc/drugs/alpelisib/>, <https://onco.cc/drugs/capivasertib/>, <https://onco.cc/drugs/inavolisib/> ;
  onco:companies <https://onco.cc/companies/mei-pharma/> .