# OnCo record pik3cd (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/pik3cd/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "pik3cd" ;
  schema:name "PI3K delta (PIK3CD)"@en ;
  schema:description "The blood-cell version of the PI3K survival signal that keeps B cells alive. Idelalisib, duvelisib and copanlisib block it in chronic lymphocytic leukaemia and follicular lymphoma, at the price of immune-related colitis, liver inflammation and infections that have limited their use."@en ;
  schema:url <https://onco.cc/targets/pik3cd/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/PIK3CD>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:8977>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000171608>, <https://www.uniprot.org/uniprotkb/O00329/entry>, <https://www.ncbi.nlm.nih.gov/gene/5293> ;
  schema:citation <https://www.uniprot.org/uniprotkb/O00329/entry> ;
  schema:alternateName "PIK3CD" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1997"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/cll/>, <https://onco.cc/cancers/follicular-lymphoma/> ;
  onco:drugs <https://onco.cc/drugs/idelalisib/>, <https://onco.cc/drugs/duvelisib/>, <https://onco.cc/drugs/copanlisib/> .