# OnCo record pipobroman (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/pipobroman/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "pipobroman" ;
  schema:name "Pipobroman"@en ;
  schema:description "Pipobroman was an oral tablet approved in 1966 for polycythaemia vera, the blood disorder that makes too many red cells, and for chronic myeloid leukaemia; it was discontinued after studies showed it raised the risk of leukaemia compared with hydroxycarbamide."@en ;
  schema:url <https://onco.cc/drugs/pipobroman/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Pipobroman> ;
  schema:citation <https://en.wikipedia.org/wiki/Pipobroman>, <https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201205> ;
  onco:status "historic" ;
  onco:tag "gap-fill", "chembl-universe" ;
  onco:modality "Oral alkylating-type cytotoxic" ;
  schema:alternateName "Vercyte" ;
  onco:approval "US 1966: Polycythaemia vera; chronic myeloid leukaemia refractory to busulfan (historic label)" ;
  onco:cancers <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/cml/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/hydroxyurea/>, <https://onco.cc/drugs/ruxolitinib/> ;
  onco:trials <https://onco.cc/trials/response/> .