# OnCo record plasmamatch (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/plasmamatch/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "plasmamatch", "NCT03182634" ;
  schema:name "plasmaMATCH"@en ;
  schema:alternateName "plasmaMATCH trial"@en, "UK plasmaMATCH"@en ;
  schema:description "plasmaMATCH showed that a blood test can find the mutations that steer treatment in advanced breast cancer as reliably as a tumour biopsy, and used it to send women straight to drugs matching rare mutations. It found real activity for neratinib in HER2-mutant and capivasertib in AKT1-mutant disease."@en ;
  schema:url <https://onco.cc/trials/plasmamatch/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03182634>, <https://doi.org/10.1016/S1470-2045(20)30444-7>, <https://doi.org/10.1158/1078-0432.CCR-23-1696>, <https://doi.org/10.1158/1078-0432.CCR-24-0651> ;
  onco:status "completed" ;
  onco:phase "2" ;
  schema:startDate "2016-12-15" ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/tnbc/> ;
  onco:technologies <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/pi3k-akt-mtor-inhibitors/>, <https://onco.cc/technologies/parp-inhibitor/>, <https://onco.cc/technologies/her2-tyrosine-kinase-inhibitors/> ;
  onco:drugs <https://onco.cc/drugs/fulvestrant/>, <https://onco.cc/drugs/neratinib/>, <https://onco.cc/drugs/capivasertib/>, <https://onco.cc/drugs/olaparib/> ;
  onco:companies <https://onco.cc/companies/guardant-health/> ;
  onco:institutions <https://onco.cc/institutions/icr-london/>, <https://onco.cc/institutions/royal-marsden/>, <https://onco.cc/institutions/cruk/> ;
  onco:terms <https://onco.cc/terms/master-protocol/>, <https://onco.cc/terms/basket-umbrella-platform/>, <https://onco.cc/terms/ctdna/> ;
  onco:people <https://onco.cc/people/nicholas-turner/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-ring-clin-cancer-res/>, <https://onco.cc/key-papers/paper-browne-clin-cancer-res/>, <https://onco.cc/key-papers/paper-plasmamatch-lancet-oncol-2020/> .