# OnCo record platinum-plus-hrd (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/platinum-plus-hrd/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "platinum-plus-hrd" ;
  schema:name "Platinum chemotherapy in HRD tumours"@en ;
  schema:description "DNA-crosslinking chemotherapy is especially effective in tumours that cannot repair double-strand breaks."@en ;
  schema:url <https://onco.cc/pairings/platinum-plus-hrd/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-018-0009-7> ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/ovarian/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/> ;
  onco:pathways <https://onco.cc/pathways/ddr/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tutt-nat-med/> ;
  onco:pairs <https://onco.cc/technologies/platinum/>, <https://onco.cc/targets/brca/> .