# OnCo record plx-66140 (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/plx-66140/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "plx-66140" ;
  schema:name "PLX-66140"@en ;
  schema:description "PLX-66140 is an experimental oral molecular glue degrader from Plexium, in preclinical development for ER-positive/HER2-negative breast cancer and CCNE1-amplified tumours."@en ;
  schema:url <https://onco.cc/drugs/plx-66140/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://plexium.com/pipeline/> ;
  onco:status "preclinical" ;
  onco:tag "pipeline" ;
  onco:modality "Oral molecular glue degrader (cereblon)" ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/> ;
  onco:targets <https://onco.cc/targets/cdk2/> ;
  onco:companies <https://onco.cc/companies/plexium/> .