# OnCo record polar-bear (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/polar-bear/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "polar-bear", "NCT04332822" ;
  schema:name "POLAR BEAR"@en ;
  schema:alternateName "POLAR BEAR trial"@en, "R-pola-miniCHP in very old patients"@en ;
  schema:description "A Nordic trial asking whether the antibody-drug conjugate that improved first-line treatment for younger patients also helps people in their eighties, who were barely represented in the original trial."@en ;
  schema:url <https://onco.cc/trials/polar-bear/> ;
  schema:dateModified "2026-10-01"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04332822> ;
  onco:status "active" ;
  onco:tag "lymphoma-evidence" ;
  onco:phase "3" ;
  schema:startDate "2020-08-19" ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/adcs/>, <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:targets <https://onco.cc/targets/cd79b/>, <https://onco.cc/targets/cd20/> ;
  onco:drugs <https://onco.cc/drugs/polatuzumab-vedotin/>, <https://onco.cc/drugs/rituximab/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/prednisone/> ;
  onco:terms <https://onco.cc/terms/r-chop/>, <https://onco.cc/terms/lymphoma-tx-regimen-alphabet/> ;
  onco:trials <https://onco.cc/trials/polarix/>, <https://onco.cc/trials/arched/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-aging-comorbidity/>, <https://onco.cc/bottlenecks/b-trial-diversity/>, <https://onco.cc/bottlenecks/b-trial-enrolment/> .