# OnCo record polarix (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/polarix/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "polarix", "NCT03274492" ;
  schema:name "POLARIX"@en ;
  schema:description "The trial that improved on R-CHOP for the first time in twenty years, by swapping vincristine for an ADC."@en ;
  schema:url <https://onco.cc/trials/polarix/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03274492>, <https://www.nejm.org/doi/full/10.1056/NEJMoa2115304>, <https://ascopubs.org/doi/10.1200/JCO-25-00925> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2017-11-16" ;
  onco:related <https://onco.cc/roadmaps/lymphoma-roadmap/>, <https://onco.cc/trials/polargo/>, <https://onco.cc/trials/polar-bear/>, <https://onco.cc/trials/flyer/>, <https://onco.cc/trials/goya/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:drugs <https://onco.cc/drugs/polatuzumab-vedotin/>, <https://onco.cc/drugs/doxorubicin/> ;
  onco:companies <https://onco.cc/companies/lysa/> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/ipi-score/> ;
  onco:people <https://onco.cc/people/gilles-salles/>, <https://onco.cc/people/herve-tilly/>, <https://onco.cc/people/laurie-sehn/> .