# OnCo record poma-sonodynamic-therapy (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/poma-sonodynamic-therapy/>
  a schema:MedicalDevice ;
  onco:kind "drug" ;
  schema:identifier "poma-sonodynamic-therapy" ;
  schema:name "PoMA sonodynamic therapy"@en ;
  schema:alternateName "Porphyrin Metabolite Activation"@en, "5-ALA HCl + LIDU SDT"@en ;
  schema:description "PoMA sonodynamic therapy is an experimental drug and ultrasound treatment from Alpheus Medical, in phase 2 trials for glioblastoma."@en ;
  schema:url <https://onco.cc/drugs/poma-sonodynamic-therapy/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://alpheusmedical.com/program-overview/>, <https://clinicaltrials.gov/study/NCT07225621>, <https://clinicaltrials.gov/study/NCT07862647>, <https://clinicaltrials.gov/study/NCT05362409> ;
  onco:status "phase-2" ;
  onco:tag "pipeline", "ctgov-ingest" ;
  onco:modality "Drug-device combination: oral 5-aminolevulinic acid activated by low-intensity defocused ultrasound (sonodynamic therapy)" ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/> ;
  onco:companies <https://onco.cc/companies/alpheus-medical/> ;
  onco:trials <https://onco.cc/trials/nct07225621/>, <https://onco.cc/trials/nct07862647/>, <https://onco.cc/trials/nct05362409/> .