# OnCo record precision-roadmap (roadmap). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/roadmaps/precision-roadmap/>
  a schema:CreativeWork ;
  onco:kind "roadmap" ;
  schema:identifier "precision-roadmap" ;
  schema:name "Precision roadmap: margins measured in millimetres → tests that find a target → doses fitted to the person → precision that changes outcomes"@en ;
  schema:alternateName "Precision in cancer care"@en, "How precise cancer treatment is"@en, "Precision oncology roadmap"@en, "Precision matrix"@en ;
  schema:description "Cancer care is limited by how precise it is: how small a tumour a test can find, how close to it a surgeon can cut, how tightly a beam can be aimed and how well a dose fits the person. This roadmap follows each of those from where it stands now to the next step, and says plainly where more precision has been shown to help a patient and where it has not."@en ;
  schema:url <https://onco.cc/roadmaps/precision-roadmap/> ;
  schema:dateModified "2026-10-20"^^xsd:date ;
  schema:citation <https://onco.cc/live/precision/>, <https://doi.org/10.1016/S0360-3016(00)00518-6>, <https://doi.org/10.1056/NEJMoa1209825>, <https://doi.org/10.1001/jamaoncol.2022.6558>, <https://doi.org/10.1056/NEJMoa1504473>, <https://doi.org/10.1016/S0140-6736(20)30314-7>, <https://doi.org/10.1056/EVIDoa2200333>, <https://doi.org/10.1200/JCO.19.03010>, <https://doi.org/10.1001/jamaoncol.2018.1660>, <https://doi.org/10.1016/S1470-2045(18)30686-7>, <https://www.fda.gov/about-fda/oncology-center-excellence/project-optimus>, <https://doi.org/10.1056/NEJMoa2200075> ;
  onco:tag "precision" ;
  onco:related <https://onco.cc/roadmaps/ctdna-tests/>, <https://onco.cc/roadmaps/radiation-roadmap/>, <https://onco.cc/roadmaps/surgery-roadmap/>, <https://onco.cc/roadmaps/molecular-imaging-roadmap/>, <https://onco.cc/roadmaps/diagnostics-roadmap/>, <https://onco.cc/ideas/idea-moon-image-guided-surgery-everywhere/>, <https://onco.cc/ideas/idea-bio2-lean-mass-dosing/>, <https://onco.cc/ideas/idea-tr1-model-based-dose-finding-with-late-toxicity/>, <https://onco.cc/ideas/idea-moon-post-approval-dose-deescalation/>, <https://onco.cc/ideas/idea-cost-optimus-legacy-drugs/>, <https://onco.cc/ideas/idea-net-dosimetry-prrt/>, <https://onco.cc/ideas/idea-bio2-functional-precision-rare/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/>, <https://onco.cc/fronts/imaging/>, <https://onco.cc/fronts/surgery/>, <https://onco.cc/fronts/radiation/>, <https://onco.cc/fronts/targeted-therapy/>, <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/respiratory-motion-management/>, <https://onco.cc/technologies/mr-linac/>, <https://onco.cc/technologies/adaptive-radiotherapy/>, <https://onco.cc/technologies/sbrt/>, <https://onco.cc/technologies/proton-therapy/>, <https://onco.cc/technologies/sentinel-node/>, <https://onco.cc/technologies/psma-pet/>, <https://onco.cc/technologies/fluorescence-guided-surgery/>, <https://onco.cc/technologies/intraoperative-fluorescence-imaging-systems/>, <https://onco.cc/technologies/digital-pathology-ai/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/companion-diagnostic/>, <https://onco.cc/technologies/variant-knowledgebases/>, <https://onco.cc/technologies/dpyd-genotyping/>, <https://onco.cc/technologies/oncology-pharmacogenomics/>, <https://onco.cc/technologies/functional-precision-medicine-haematology/> ;
  onco:drugs <https://onco.cc/drugs/pegulicianine/>, <https://onco.cc/drugs/signatera/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/capecitabine/>, <https://onco.cc/drugs/sotorasib/> ;
  onco:terms <https://onco.cc/terms/deep-inspiration-breath-hold/>, <https://onco.cc/terms/breast-margins-and-re-excision/>, <https://onco.cc/terms/resection-margins/>, <https://onco.cc/terms/ngs/>, <https://onco.cc/terms/tumour-agnostic/>, <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/project-optimus/>, <https://onco.cc/terms/hypofractionation/> ;
  onco:trials <https://onco.cc/trials/nci-match/>, <https://onco.cc/trials/propsma/>, <https://onco.cc/trials/dynamic/>, <https://onco.cc/trials/imvigor011/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dose-optimisation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-flaherty-j-clin-oncol/>, <https://onco.cc/key-papers/paper-kishan-jama-oncol/>, <https://onco.cc/key-papers/paper-propsma-hofman-lancet-2020/>, <https://onco.cc/key-papers/paper-henricks-lancet-oncol/> .