# OnCo record preempt-crc (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/preempt-crc/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "preempt-crc", "NCT04369053" ;
  schema:name "PREEMPT CRC"@en ;
  schema:alternateName "FRNM-004"@en, "Prevention of Colorectal Cancer Through Multiomics Blood Testing"@en ;
  schema:description "The study behind the second approved blood test for bowel cancer screening: the test found about four in five cancers and kept false alarms low, but like Shield it missed most advanced polyps, which is why guidelines still rank blood tests below colonoscopy and stool tests."@en ;
  schema:url <https://onco.cc/trials/preempt-crc/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04369053>, <https://doi.org/10.1001/jama.2025.7515> ;
  onco:status "positive" ;
  onco:phase "observational" ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/colorectal-screening/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/methylation-profiling/> ;
  onco:drugs <https://onco.cc/drugs/simplescreen-crc/> ;
  onco:companies <https://onco.cc/companies/freenome/> ;
  onco:terms <https://onco.cc/terms/cfdna/>, <https://onco.cc/terms/sensitivity-specificity/>, <https://onco.cc/terms/screening/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-preempt-crc-shaukat-jama-2025/> .