# OnCo record prevail (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/prevail/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "prevail", "NCT01212991" ;
  schema:name "PREVAIL"@en ;
  schema:alternateName "PREVAIL"@en, "MDV3100-04"@en ;
  schema:description "Moved enzalutamide in front of chemotherapy, cutting the risk of the cancer showing on scans by four fifths and the risk of death by a third."@en ;
  schema:url <https://onco.cc/trials/prevail/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01212991>, <https://doi.org/10.1056/NEJMoa1405095>, <https://www.nice.org.uk/guidance/ta377> ;
  onco:status "positive" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/androgen-deprivation/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/> ;
  onco:drugs <https://onco.cc/drugs/enzalutamide/> ;
  onco:companies <https://onco.cc/companies/astellas/>, <https://onco.cc/companies/pfizer/> ;
  onco:terms <https://onco.cc/terms/arpi/>, <https://onco.cc/terms/castration-resistance/>, <https://onco.cc/terms/psa50/> ;
  onco:trials <https://onco.cc/trials/affirm/>, <https://onco.cc/trials/cou-aa-302/> .