# OnCo record prex2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/prex2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "prex2" ;
  schema:name "PREX2"@en ;
  schema:alternateName "phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2"@en, "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein"@en, "DEP.2"@en, "FLJ12987"@en, "P-REX2"@en, "PPP1R129"@en, "DEPDC2"@en, "PREX2" ;
  schema:description "PREX2 is a gene that drives cell growth when it is altered. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response."@en ;
  schema:url <https://onco.cc/targets/prex2/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:22950>, <https://www.uniprot.org/uniprotkb/Q70Z35/entry>, <https://www.ncbi.nlm.nih.gov/gene/80243>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000046889> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "oncogene" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:22950>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000046889>, <https://www.uniprot.org/uniprotkb/Q70Z35/entry>, <https://www.ncbi.nlm.nih.gov/gene/80243> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/pancreatic/> .