# OnCo record prima-cns (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/prima-cns/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "prima-cns", "NCT06830421" ;
  schema:name "PRIMA-CNS"@en ;
  schema:alternateName "PRIMA-CNS trial"@en, "R-MP versus MARTA with transplant in elderly primary CNS lymphoma"@en ;
  schema:description "The first randomised trial asking whether older people with lymphoma of the brain do better with a short intensive course and a stem cell transplant than with the gentler long regimen that is standard in Germany."@en ;
  schema:url <https://onco.cc/trials/prima-cns/> ;
  schema:dateModified "2026-10-01"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT06830421> ;
  onco:status "active" ;
  onco:tag "lymphoma-evidence" ;
  onco:phase "3" ;
  schema:startDate "2023-08-09" ;
  onco:cancers <https://onco.cc/cancers/primary-cns-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/chemotherapy/>, <https://onco.cc/fronts/cell-therapy/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/cd20/> ;
  onco:drugs <https://onco.cc/drugs/rituximab/>, <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/procarbazine/>, <https://onco.cc/drugs/cytarabine/> ;
  onco:companies <https://onco.cc/companies/ielsg/> ;
  onco:terms <https://onco.cc/terms/autologous-transplant/>, <https://onco.cc/terms/lymphoma-tx-transplant-role/> ;
  onco:trials <https://onco.cc/trials/ielsg32/>, <https://onco.cc/trials/ielsg43/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-aging-comorbidity/>, <https://onco.cc/bottlenecks/b-rare-cancers/> .