# OnCo record prime-ii (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/prime-ii/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "prime-ii" ;
  schema:name "PRIME II"@en ;
  schema:description "PRIME II confirmed in a larger and more recent population that omitting radiotherapy in older women with low-risk hormone-sensitive breast cancer raises local recurrence modestly without affecting survival."@en ;
  schema:url <https://onco.cc/trials/prime-ii/> ;
  schema:dateModified "2026-09-16"^^xsd:date ;
  schema:citation <https://www.isrctn.com/ISRCTN95889329>, <https://doi.org/10.1056/NEJMoa2207586> ;
  onco:status "positive" ;
  onco:tag "radiation-wave2" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/active-surveillance/> ;
  onco:terms <https://onco.cc/terms/radiotherapy-omission-early-breast-cancer/> ;
  onco:trials <https://onco.cc/trials/calgb-9343/>, <https://onco.cc/trials/lumina/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-kunkler-n-engl-j-med/> .