# OnCo record procarbazine (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/procarbazine/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "procarbazine" ;
  schema:name "Procarbazine"@en ;
  schema:alternateName "Natulan"@en, "Matulane" ;
  schema:description "Procarbazine (Matulane) is an old chemotherapy capsule from the MOPP regimen for Hodgkin lymphoma; it is now used mainly in the PCV combination for certain brain tumours."@en ;
  schema:url <https://onco.cc/drugs/procarbazine/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Procarbazine> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=procarbazine>, <https://www.cancer.gov/about-cancer/treatment/drugs/procarbazinehydrochloride> ;
  onco:status "approved" ;
  onco:tag "nci-list" ;
  onco:modality "Alkylating-like methylhydrazine derivative" ;
  onco:approval "US 1969: Stage III and IV Hodgkin disease in combination (MOPP)" ;
  onco:related <https://onco.cc/drugs/lomustine/> ;
  onco:cancers <https://onco.cc/cancers/hodgkin-lymphoma/>, <https://onco.cc/cancers/glioblastoma/>, <https://onco.cc/cancers/oligodendroglioma/>, <https://onco.cc/cancers/idh-mutant-astrocytoma/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:companies <https://onco.cc/companies/leadiant/> ;
  onco:trials <https://onco.cc/trials/rtog-9402/>, <https://onco.cc/trials/eortc-26951/>, <https://onco.cc/trials/nct07015242/> .