# OnCo record prosigna (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/prosigna/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "prosigna" ;
  schema:name "Prosigna (PAM50)"@en ;
  schema:description "A 50-gene test run in local hospital laboratories that estimates the ten-year risk of a hormone-positive breast cancer coming back."@en ;
  schema:url <https://onco.cc/drugs/prosigna/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm?ID=K130010>, <https://www.nice.org.uk/guidance/dg34> ;
  onco:status "approved" ;
  onco:tag "test" ;
  onco:modality "Gene-expression prognostic assay (50-gene PAM50 risk of recurrence)" ;
  schema:alternateName "Prosigna" ;
  onco:approval "US 2013: Prognosis of distant recurrence in postmenopausal HR+ early breast cancer (510(k))", "EU 2012: CE-IVD" ;
  onco:related <https://onco.cc/drugs/oncotype-dx/>, <https://onco.cc/drugs/mammaprint/>, <https://onco.cc/drugs/endopredict/> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/rna-seq/> ;
  onco:companies <https://onco.cc/companies/veracyte/> ;
  onco:terms <https://onco.cc/terms/biomarker/> ;
  onco:trials <https://onco.cc/trials/nct02653755/> .