# OnCo record prostate-adt-burden (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/prostate-adt-burden/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "prostate-adt-burden" ;
  schema:name "What androgen deprivation costs: the side of hormone therapy the survival curves do not show"@en ;
  schema:alternateName "ADT side effects"@en, "hormone therapy burden prostate"@en, "castration side effects"@en ;
  schema:description "Hormone therapy for prostate cancer works by removing testosterone, which means hot flushes, loss of sexual desire and erections, tiredness, loss of muscle, weaker bones and a changed body. Trials measure it, and it is the reason the duration question matters so much."@en ;
  schema:url <https://onco.cc/terms/prostate-adt-burden/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa0810095>, <https://doi.org/10.1016/S0140-6736(24)00549-X>, <https://doi.org/10.1056/NEJMoa1212299>, <https://doi.org/10.1016/S0140-6736(21)00100-8>, <https://www.nice.org.uk/guidance/ta995> ;
  onco:status "established" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mhspc/>, <https://onco.cc/cancers/prostate-high-risk/>, <https://onco.cc/cancers/prostate-nmcrpc/> ;
  onco:technologies <https://onco.cc/technologies/androgen-deprivation/> ;
  onco:drugs <https://onco.cc/drugs/relugolix/>, <https://onco.cc/drugs/degarelix/>, <https://onco.cc/drugs/goserelin/>, <https://onco.cc/drugs/leuprolide/> ;
  onco:terms <https://onco.cc/terms/adt/>, <https://onco.cc/terms/hormone-therapy/>, <https://onco.cc/terms/qol-pro/>, <https://onco.cc/terms/bone-metastases/> ;
  onco:trials <https://onco.cc/trials/eortc-22961/>, <https://onco.cc/trials/rtog-9202/>, <https://onco.cc/trials/dart-01-05-gicor/>, <https://onco.cc/trials/radicals-hd/>, <https://onco.cc/trials/swog-9346/>, <https://onco.cc/trials/patch-transdermal-oestradiol/> .