# OnCo record prostate-crpc-sequencing (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/prostate-crpc-sequencing/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "prostate-crpc-sequencing" ;
  schema:name "What follows what in castration-resistant prostate cancer"@en ;
  schema:alternateName "mCRPC sequencing"@en, "prostate cancer treatment order"@en, "hormone-relapsed prostate cancer sequence"@en ;
  schema:description "Once prostate cancer stops responding to standard hormone therapy there are six or seven things left to try, and the order matters. The one rule proved by a trial is that swapping one hormone tablet for another, after the first stopped working quickly, is a waste of time."@en ;
  schema:url <https://onco.cc/terms/prostate-crpc-sequencing/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1911206>, <https://doi.org/10.1056/NEJMoa2214676>, <https://doi.org/10.1016/j.annonc.2026.02.009>, <https://uroweb.org/guidelines/prostate-cancer> ;
  onco:status "established" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/androgen-deprivation/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/parp-inhibitor/>, <https://onco.cc/technologies/lu177-radioligand-therapy/>, <https://onco.cc/technologies/targeted-alpha-therapy/>, <https://onco.cc/technologies/psma-pet/> ;
  onco:terms <https://onco.cc/terms/castration-resistance/>, <https://onco.cc/terms/arpi/>, <https://onco.cc/terms/hrd/>, <https://onco.cc/terms/mcrpc-mhspc/> ;
  onco:trials <https://onco.cc/trials/card/>, <https://onco.cc/trials/tax-327/>, <https://onco.cc/trials/tropic/>, <https://onco.cc/trials/proselica/>, <https://onco.cc/trials/cou-aa-301/>, <https://onco.cc/trials/cou-aa-302/>, <https://onco.cc/trials/affirm/>, <https://onco.cc/trials/prevail/>, <https://onco.cc/trials/triton3/>, <https://onco.cc/trials/vision/>, <https://onco.cc/trials/psmafore/>, <https://onco.cc/trials/therap/>, <https://onco.cc/trials/alsympca/>, <https://onco.cc/trials/peace-3/> .