# OnCo record protac-degrader (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/protac-degrader/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "protac-degrader" ;
  schema:name "PROTACs & molecular glues (targeted protein degradation)"@en ;
  schema:description "Instead of blocking a protein, these drugs tag it for the cell's own garbage disposal, removing it entirely."@en ;
  schema:url <https://onco.cc/technologies/protac-degrader/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Proteolysis_targeting_chimera> ;
  owl:sameAs <http://www.wikidata.org/entity/Q25324636> ;
  schema:citation <https://en.wikipedia.org/wiki/Proteolysis_targeting_chimera> ;
  onco:status "approved" ;
  onco:related <https://onco.cc/ideas/idea-senolytics-after-chemo/>, <https://onco.cc/companies/stablix/> ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/> ;
  onco:technologies <https://onco.cc/technologies/degrader-antibody-conjugate/> ;
  onco:targets <https://onco.cc/targets/estrogen-receptor/>, <https://onco.cc/targets/androgen-receptor/>, <https://onco.cc/targets/kras/> ;
  onco:drugs <https://onco.cc/drugs/vepdegestrant/> ;
  onco:companies <https://onco.cc/companies/arvinas/>, <https://onco.cc/companies/pfizer/>, <https://onco.cc/companies/bms/>, <https://onco.cc/companies/amphista-therapeutics/>, <https://onco.cc/companies/boundless-bio/>, <https://onco.cc/companies/captor-therapeutics/>, <https://onco.cc/companies/cullgen/>, <https://onco.cc/companies/firefly-bio/>, <https://onco.cc/companies/foghorn-therapeutics/>, <https://onco.cc/companies/neomorph/>, <https://onco.cc/companies/orum-therapeutics/>, <https://onco.cc/companies/photys-therapeutics/>, <https://onco.cc/companies/plexium/>, <https://onco.cc/companies/prelude-therapeutics/>, <https://onco.cc/companies/proxygen/>, <https://onco.cc/companies/treeline-biosciences/>, <https://onco.cc/companies/triana-biomedicines/> .