# OnCo record prps1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/prps1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "prps1" ;
  schema:name "PRPS1"@en ;
  schema:alternateName "phosphoribosyl pyrophosphate synthetase 1"@en, "Ribose-phosphate pyrophosphokinase 1"@en, "CMTX5"@en, "DFNX1"@en, "PRS-I"@en, "PPRibP"@en, "DFN2"@en, "PRPS1" ;
  schema:description "PRPS1 (Ribose-phosphate pyrophosphokinase 1) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Acute lymphoblastic leukaemia."@en ;
  schema:url <https://onco.cc/targets/prps1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9462>, <https://www.uniprot.org/uniprotkb/P60891/entry>, <https://www.ncbi.nlm.nih.gov/gene/5631>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000147224> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9462>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000147224>, <https://www.uniprot.org/uniprotkb/P60891/entry>, <https://www.ncbi.nlm.nih.gov/gene/5631> ;
  onco:related <https://onco.cc/collections/civic/> ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/> .