# OnCo record pvr (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/pvr/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "pvr" ;
  schema:name "CD155 (PVR)"@en ;
  schema:alternateName "CD155"@en, "poliovirus receptor"@en, "Necl-5"@en, "NECL5"@en, "PVS"@en, "PVR" ;
  schema:description "CD155 is the molecule on tumour cells that TIGIT and CD96 read; normal tissue barely shows it, many tumours show a lot. Every TIGIT antibody works by breaking the CD155 handshake."@en ;
  schema:url <https://onco.cc/targets/pvr/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9705>, <https://www.uniprot.org/uniprotkb/P15151/entry>, <https://www.ncbi.nlm.nih.gov/gene/5817>, <https://europepmc.org/article/MED/28730595> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "checkpoint" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9705>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000073008>, <https://www.uniprot.org/uniprotkb/P15151/entry>, <https://www.ncbi.nlm.nih.gov/gene/5817> ;
  onco:related <https://onco.cc/targets/tigit/>, <https://onco.cc/targets/cd96/>, <https://onco.cc/targets/nectin2/>, <https://onco.cc/drugs/tiragolumab/> ;
  onco:technologies <https://onco.cc/technologies/tigit-blockade/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/> .