# OnCo record rad51-foci-assay (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rad51-foci-assay/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rad51-foci-assay" ;
  schema:name "RAD51 foci assay (functional HRD test)"@en ;
  schema:alternateName "RAD51 assay"@en, "RAD51 immunofluorescence"@en, "functional homologous recombination test"@en ;
  schema:description "A microscope test on an ordinary tumour biopsy that counts RAD51 repair spots in dividing cells; few spots means the tumour cannot repair DNA by homologous recombination right now, which is what PARP inhibitors exploit."@en ;
  schema:url <https://onco.cc/technologies/rad51-foci-assay/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.15252/emmm.201809172> ;
  onco:status "emerging" ;
  onco:related <https://onco.cc/technologies/companion-diagnostic/>, <https://onco.cc/companies/intodna/>, <https://onco.cc/bottlenecks/b-biomarker-validation/> ;
  onco:cancers <https://onco.cc/cancers/high-grade-serous-ovarian-cancer/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/prostate/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/hrd-testing/>, <https://onco.cc/technologies/hrd-genomic-scar-scores/>, <https://onco.cc/technologies/stride-dna-break-detection/>, <https://onco.cc/technologies/parp-inhibitor/>, <https://onco.cc/technologies/histopathology-ihc/> ;
  onco:targets <https://onco.cc/targets/brca/>, <https://onco.cc/targets/parp/> ;
  onco:drugs <https://onco.cc/drugs/olaparib/>, <https://onco.cc/drugs/niraparib/>, <https://onco.cc/drugs/rucaparib/>, <https://onco.cc/drugs/talazoparib/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/cisplatin/> ;
  onco:terms <https://onco.cc/terms/hrd/> .