# OnCo record raf1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/raf1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "raf1" ;
  schema:name "CRAF (RAF1)"@en ;
  schema:description "CRAF is BRAF's sibling in the growth-signal relay; sorafenib and regorafenib were designed against it, and it is the route by which RAS-mutant tumours escape BRAF-only drugs."@en ;
  schema:url <https://onco.cc/targets/raf1/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/C-Raf>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9829>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000132155>, <https://www.uniprot.org/uniprotkb/P04049/entry>, <https://www.ncbi.nlm.nih.gov/gene/5894> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P04049/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9829>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL1906> ;
  schema:alternateName "RAF1" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1985"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/braf/>, <https://onco.cc/targets/mek/> ;
  onco:cancers <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/colorectal/> ;
  onco:drugs <https://onco.cc/drugs/sorafenib/>, <https://onco.cc/drugs/regorafenib/> .