# OnCo record ramucirumab (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/ramucirumab/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "ramucirumab" ;
  schema:name "Ramucirumab"@en ;
  schema:description "An antibody that blocks the VEGF receptor, approved in liver cancer only for patients with a high AFP blood level, the first biomarker-selected HCC drug."@en ;
  schema:url <https://onco.cc/drugs/ramucirumab/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Ramucirumab> ;
  owl:sameAs <http://www.wikidata.org/entity/Q7290345> ;
  schema:citation <https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/125477s040lbl.pdf>, <https://www.nice.org.uk/guidance/ta403> ;
  onco:status "approved" ;
  onco:modality "Monoclonal antibody (anti-VEGFR2)" ;
  schema:alternateName "Cyramza" ;
  onco:approval "US 2014: Gastric cancer; NSCLC", "US 2019: HCC with AFP ≥400 ng/mL after sorafenib", "England (NICE) 2016: Locally advanced or metastatic non-small-cell lung cancer progressing after platinum-based chemotherapy, with docetaxel: not recommended" ;
  onco:cancers <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/lung-cancer/> ;
  onco:technologies <https://onco.cc/technologies/monoclonal-antibody/>, <https://onco.cc/technologies/antiangiogenic/> ;
  onco:targets <https://onco.cc/targets/vegf/> ;
  onco:companies <https://onco.cc/companies/eli-lilly/> ;
  onco:pathways <https://onco.cc/pathways/vegf-angiogenesis/> ;
  onco:terms <https://onco.cc/terms/afp/> ;
  onco:trials <https://onco.cc/trials/nct02411448/>, <https://onco.cc/trials/nct06448754/>, <https://onco.cc/trials/nct07098338/>, <https://onco.cc/trials/nct06996782/>, <https://onco.cc/trials/nct06038578/>, <https://onco.cc/trials/nct05999994/>, <https://onco.cc/trials/nct06771622/>, <https://onco.cc/trials/nct05190445/>, <https://onco.cc/trials/nct06445972/>, <https://onco.cc/trials/nct06123494/>, <https://onco.cc/trials/rainbow/>, <https://onco.cc/trials/destiny-gastric04/>, <https://onco.cc/trials/raise/>, <https://onco.cc/trials/lung-map-s1800a/> .