# OnCo record rankl (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/rankl/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "rankl" ;
  schema:name "RANK ligand (RANKL)"@en ;
  schema:description "RANK ligand is the signal that tells bone-dissolving cells to get to work. Cancers in the bone hijack it; denosumab blocks it to prevent fractures and other bone complications."@en ;
  schema:url <https://onco.cc/targets/rankl/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/RANKL>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11926>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000120659>, <https://www.uniprot.org/uniprotkb/O14788/entry>, <https://www.ncbi.nlm.nih.gov/gene/8600> ;
  schema:citation <https://www.ncbi.nlm.nih.gov/gene/8600> ;
  onco:tag "bone" ;
  schema:alternateName "TNFSF11" ;
  onco:targetClass "stroma" ;
  onco:firstDescribed "1997"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/multiple-myeloma/> ;
  onco:technologies <https://onco.cc/technologies/bone-modifying-agents/> ;
  onco:drugs <https://onco.cc/drugs/denosumab/> .