# OnCo record realgar-indigo-naturalis (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/realgar-indigo-naturalis/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "realgar-indigo-naturalis" ;
  schema:name "Realgar-indigo naturalis formulation"@en ;
  schema:alternateName "realgar-indigo naturalis formula"@en, "realgar-indigo naturalis"@en, "RIF"@en, "tetra-arsenic tetra-sulfide"@en ;
  schema:description "Realgar-indigo naturalis is an arsenic medicine taken by mouth, developed in China, for acute promyelocytic leukaemia. It does the same job as arsenic trioxide, which is given by drip, and the WHO lists it as an essential medicine."@en ;
  schema:url <https://onco.cc/drugs/realgar-indigo-naturalis/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://list.essentialmeds.org/medicines/555>, <https://doi.org/10.3324/haematol.2024.285905>, <https://doi.org/10.1073/pnas.0712365105> ;
  onco:tag "universe-gap", "who-eml" ;
  onco:modality "Inorganic arsenical (differentiation agent)" ;
  onco:approval "WHO 2019: Essential Medicines List, cytotoxic medicines: acute myeloid leukaemia with recurrent genetic abnormalities (acute promyelocytic leukaemia)" ;
  onco:related <https://onco.cc/drugs/arsenic-trioxide/>, <https://onco.cc/drugs/tretinoin-atra/>, <https://onco.cc/technologies/traditional-chinese-herbal-medicine/> ;
  onco:cancers <https://onco.cc/cancers/apl/>, <https://onco.cc/cancers/aml/> ;
  onco:targets <https://onco.cc/targets/rara/> .