# OnCo record recombinant-human-endostatin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/recombinant-human-endostatin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "recombinant-human-endostatin" ;
  schema:name "Recombinant human endostatin"@en ;
  schema:alternateName "Endostar"@en, "rh-endostatin"@en ;
  schema:description "Endostar is Simcere's recombinant endostatin, approved in China in 2005 with chemotherapy for advanced non-small-cell lung cancer, one of the first angiogenesis inhibitors approved anywhere."@en ;
  schema:url <https://onco.cc/drugs/recombinant-human-endostatin/> ;
  schema:dateModified "2026-09-16"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/search?intr=Endostar> ;
  onco:status "approved" ;
  onco:tag "china", "nmpa-approved" ;
  onco:modality "Recombinant angiogenesis inhibitor protein" ;
  onco:approval "CN 2005: Advanced non-small-cell lung cancer, with vinorelbine and cisplatin" ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:companies <https://onco.cc/companies/simcere/> ;
  onco:trials <https://onco.cc/trials/nct00576914/>, <https://onco.cc/trials/nct01124253/>, <https://onco.cc/trials/nct02579564/> .