# OnCo record rejuv-age-frailty-and-late-effects (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-age-frailty-and-late-effects/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-age-frailty-and-late-effects" ;
  schema:name "Frailty and late effects in survivors"@en ;
  schema:description "The clearest evidence that treatment ages people is not a laboratory marker, it is what happens to survivors decades later. In the St Jude Lifetime Cohort, one in eight women who had cancer as a child met the clinical definition of frailty at a mean age of 33, a rate usually seen after 65. Frailty predicted new chronic conditions and death."@en ;
  schema:url <https://onco.cc/technologies/rejuv-age-frailty-and-late-effects/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Frailty_syndrome> ;
  schema:citation <https://doi.org/10.1200/JCO.2013.52.2268>, <https://doi.org/10.1001/jama.2013.6296>, <https://doi.org/10.1056/NEJMsa060185>, <https://doi.org/10.1016/S1470-2045(25)00157-3> ;
  onco:status "established" ;
  onco:tag "rejuvenation", "survivorship", "biological-ageing", "late-effects", "childhood-cancer" ;
  onco:related <https://onco.cc/technologies/rejuv-age-epigenetic-clocks/>, <https://onco.cc/technologies/rejuv-age-senescent-cells-after-treatment/>, <https://onco.cc/technologies/rejuv-frontier-what-works/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/survivorship-care-plan/>, <https://onco.cc/technologies/exercise-oncology/>, <https://onco.cc/terms/second-cancers-after-radiotherapy/>, <https://onco.cc/technologies/prehabilitation/> ;
  onco:terms <https://onco.cc/terms/late-effects/>, <https://onco.cc/terms/quality-of-life/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-survivorship/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-schaapveld-second-cancer-risk-40-years-hodgkin-nejm-2015/> .