# OnCo record rejuv-agenda-biological-age-as-an-untested-target (bottleneck). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/bottlenecks/rejuv-agenda-biological-age-as-an-untested-target/>
  a schema:Thing ;
  onco:kind "bottleneck" ;
  schema:identifier "rejuv-agenda-biological-age-as-an-untested-target" ;
  schema:name "Nobody has tested whether reversing measured biological ageing changes anything"@en ;
  schema:description "Cancer treatment measurably accelerates several markers of biological ageing. No trial has ever asked whether moving one of those markers makes any difference to a person, and an entire retail industry rests on the assumption that it would."@en ;
  schema:url <https://onco.cc/bottlenecks/rejuv-agenda-biological-age-as-an-untested-target/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:citation <https://doi.org/10.1093/jnci/djaa147>, <https://doi.org/10.1200/JCO.2013.52.2268>, <https://clinicaltrials.gov/study/NCT06113016> ;
  onco:tag "rejuvenation", "survivorship", "open-problem", "biological-ageing" ;
  onco:related <https://onco.cc/technologies/rejuv-age-epigenetic-clocks/>, <https://onco.cc/technologies/rejuv-age-senescent-cells-after-treatment/>, <https://onco.cc/technologies/rejuv-age-telomere-length/>, <https://onco.cc/technologies/rejuv-age-frailty-and-late-effects/>, <https://onco.cc/technologies/rejuv-frontier-senolytics/>, <https://onco.cc/technologies/rejuv-frontier-metformin-ageing/>, <https://onco.cc/technologies/rejuv-frontier-rapamycin-ageing/>, <https://onco.cc/technologies/rejuv-frontier-nad-precursors/>, <https://onco.cc/technologies/rejuv-frontier-what-works/>, <https://onco.cc/ideas/idea-rejuv-biological-age-as-a-randomised-endpoint/>, <https://onco.cc/trials/rejuv-trial-proffi/>, <https://onco.cc/roadmaps/rejuvenation-roadmap/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> .