# OnCo record rejuv-agenda-thymus-does-not-regrow (bottleneck). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/bottlenecks/rejuv-agenda-thymus-does-not-regrow/>
  a schema:Thing ;
  onco:kind "bottleneck" ;
  schema:identifier "rejuv-agenda-thymus-does-not-regrow" ;
  schema:name "Nothing in routine use rebuilds an adult's thymus"@en ;
  schema:description "After a transplant or intensive chemotherapy, the part of the immune system that makes new kinds of T cell recovers slowly in adults and sometimes not at all. The deficit is well described, well measured and currently not correctable."@en ;
  schema:url <https://onco.cc/bottlenecks/rejuv-agenda-thymus-does-not-regrow/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S1473-3099(18)30600-5> ;
  onco:tag "rejuvenation", "survivorship", "open-problem", "immune" ;
  onco:related <https://onco.cc/technologies/rejuv-tx-immune-reconstitution-timeline/>, <https://onco.cc/technologies/rejuv-tx-revaccination/>, <https://onco.cc/technologies/rejuv-tx-b-cell-aplasia-and-immunoglobulin/>, <https://onco.cc/technologies/rejuv-tx-infection-by-phase/>, <https://onco.cc/technologies/rejuv-frontier-immune-reconstitution/>, <https://onco.cc/ideas/idea-rejuv-thymic-regeneration-in-adults/>, <https://onco.cc/roadmaps/rejuvenation-roadmap/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> .