# OnCo record rejuv-frontier-metformin-ageing (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-frontier-metformin-ageing/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-frontier-metformin-ageing" ;
  schema:name "Metformin as an anti-ageing drug after cancer"@en ;
  schema:description "Metformin is cheap, old and safe enough that it is the obvious candidate for a drug that slows ageing. The largest cancer trial ever run on it, in 3,649 women with breast cancer, found nothing. The trial designed to test whether it slows ageing itself has not been run."@en ;
  schema:url <https://onco.cc/technologies/rejuv-frontier-metformin-ageing/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Metformin> ;
  schema:citation <https://doi.org/10.1001/jama.2022.6147>, <https://doi.org/10.1111/acel.12723> ;
  onco:status "phase-3" ;
  onco:tag "rejuvenation", "survivorship", "evidence:insufficient", "repurposing" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/survivorship-care-plan/> ;
  onco:terms <https://onco.cc/terms/late-effects/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-survivorship/> .