# OnCo record rejuv-frontier-senolytics (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-frontier-senolytics/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-frontier-senolytics" ;
  schema:name "Senolytics after cancer treatment"@en ;
  schema:description "Senolytics are drugs meant to kill the worn-out cells that chemotherapy leaves behind. The idea is good and the animal work is striking. The human evidence is four small trials in other diseases, none in cancer survivors, and the one properly randomised trial missed its main target. Nobody should be buying these."@en ;
  schema:url <https://onco.cc/technologies/rejuv-frontier-senolytics/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Senolytic> ;
  schema:citation <https://doi.org/10.1038/s41591-024-03096-2>, <https://doi.org/10.1016/j.ebiom.2018.12.052>, <https://doi.org/10.1016/j.ebiom.2019.08.069>, <https://doi.org/10.1002/cncr.33112> ;
  onco:status "phase-2" ;
  onco:tag "rejuvenation", "survivorship", "evidence:insufficient", "senescence" ;
  onco:related <https://onco.cc/ideas/idea-senolytics-after-chemo/>, <https://onco.cc/ideas/idea-bio1-senolytics-after-therapy/>, <https://onco.cc/technologies/rejuv-age-senescent-cells-after-treatment/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/survivorship-care-plan/> ;
  onco:drugs <https://onco.cc/drugs/dasatinib/>, <https://onco.cc/drugs/navitoclax/> ;
  onco:pathways <https://onco.cc/pathways/senescence/>, <https://onco.cc/terms/senescent-cells/> ;
  onco:terms <https://onco.cc/terms/late-effects/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-survivorship/> .