# OnCo record rejuv-paed-bone (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-paed-bone/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-paed-bone" ;
  schema:name "Bone after childhood cancer: peak bone mass, osteonecrosis and what rebuilds"@en ;
  schema:description "A child treated during the years in which bone is laid down may never reach the peak bone mass they would have had, which is a different problem from an adult losing bone already built. Thirty per cent of adult survivors of childhood leukaemia had low bone density, most strongly associated with growth hormone deficiency and smoking, both treatable."@en ;
  schema:url <https://onco.cc/technologies/rejuv-paed-bone/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Osteoporosis> ;
  schema:citation <https://doi.org/10.1200/JCO.2015.64.9525>, <https://doi.org/10.1542/peds.2007-1396>, <https://doi.org/10.1002/jha2.70263>, <https://doi.org/10.1001/jama.2013.6296>, <https://www.ighg.org/guidelines/> ;
  onco:status "established" ;
  onco:tag "rejuvenation", "survivorship", "paediatric", "late-effects", "evidence:moderate" ;
  onco:related <https://onco.cc/collections/sjlife/>, <https://onco.cc/collections/ighg/>, <https://onco.cc/technologies/rejuv-age-frailty-and-late-effects/> ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/all-paediatric-standard-risk/>, <https://onco.cc/cancers/all-paediatric-high-risk/>, <https://onco.cc/cancers/childhood-cancers/>, <https://onco.cc/cancers/hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/cancer-treatment-bone-loss/>, <https://onco.cc/technologies/bone-modifying-agents/>, <https://onco.cc/technologies/rejuv-paed-growth-and-height/>, <https://onco.cc/technologies/rejuv-paed-pituitary-and-puberty/>, <https://onco.cc/technologies/exercise-prescription-after-cancer/>, <https://onco.cc/technologies/rejuv-paed-cog-ltfu-guidelines/> ;
  onco:drugs <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/denosumab/> ;
  onco:terms <https://onco.cc/terms/late-effects/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-survivorship/> .