# OnCo record rejuv-recovery-cumulative-dose (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-recovery-cumulative-dose/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-recovery-cumulative-dose" ;
  schema:name "The cumulative dose that decides whether it comes back"@en ;
  schema:description "For several treatments there is a published number above which lasting damage becomes much likelier: the total anthracycline dose and heart failure, the total cisplatin dose and hearing, the radiation dose to the parotid gland and dry mouth. Twenty-three thresholds are listed with their sources, because the total you have had is a question your team can answer."@en ;
  schema:url <https://onco.cc/technologies/rejuv-recovery-cumulative-dose/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Cumulative_dose> ;
  schema:citation <https://doi.org/10.1002/cncr.11407>, <https://doi.org/10.1016/j.ijrobp.2009.06.090>, <https://doi.org/10.1056/NEJMoa1209825>, <https://doi.org/10.1016/S1470-2045(14)70408-5>, <https://doi.org/10.1016/j.ijrobp.2004.11.038> ;
  onco:status "established" ;
  onco:tag "rejuvenation", "survivorship", "evidence:strong", "late-effects" ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/testicular/>, <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/hodgkin-lymphoma/>, <https://onco.cc/cancers/sarcoma/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/>, <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/anthracycline-cardioprotection/>, <https://onco.cc/technologies/hearing-after-platinum-chemotherapy/>, <https://onco.cc/technologies/fertility-preservation/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/rejuv-recovery-matrix/> ;
  onco:drugs <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/bleomycin/>, <https://onco.cc/drugs/carmustine/> ;
  onco:terms <https://onco.cc/terms/late-effects/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-survivorship/> .