# OnCo record rejuv-second-age-smoking-and-inherited-risk (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/rejuv-second-age-smoking-and-inherited-risk/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "rejuv-second-age-smoking-and-inherited-risk" ;
  schema:name "Age, smoking and inherited predisposition: what the treatment risk is added to"@en ;
  schema:alternateName "Smoking after cancer treatment"@en, "Family history and second cancers"@en, "Genetic predisposition to second cancers"@en ;
  schema:description "Treatment is rarely the only cause of a second cancer, and in adults it is usually not the main one. Smoking is the clearest example: after chest radiotherapy for Hodgkin lymphoma, the risks from tobacco and from treatment appeared to multiply rather than add, which makes stopping smoking the largest single lever a survivor has over this particular risk."@en ;
  schema:url <https://onco.cc/terms/rejuv-second-age-smoking-and-inherited-risk/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Carcinogenesis> ;
  schema:citation <https://doi.org/10.1093/jnci/94.3.182>, <https://doi.org/10.1016/S1470-2045(11)70061-4>, <https://doi.org/10.1002/ijc.22414>, <https://www.gov.uk/government/publications/breast-screening-higher-risk-women-surveillance-protocols/tests-and-frequency-of-testing-for-women-at-very-high-risk--2> ;
  onco:tag "rejuvenation", "survivorship", "second-cancers", "prevention", "smoking" ;
  onco:related <https://onco.cc/terms/rejuv-second-cancers-overview/>, <https://onco.cc/terms/second-primary-lung-after-chest-radiotherapy/>, <https://onco.cc/technologies/rejuv-age-frailty-and-late-effects/>, <https://onco.cc/terms/rejuv-second-screening-after-treatment-compared/> ;
  onco:cancers <https://onco.cc/cancers/hodgkin-lymphoma/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/cll/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/>, <https://onco.cc/fronts/prevention/> ;
  onco:technologies <https://onco.cc/terms/smoking-cessation/>, <https://onco.cc/technologies/survivorship-care-plan/> ;
  onco:terms <https://onco.cc/terms/secondary-malignancy/>, <https://onco.cc/terms/late-effects/>, <https://onco.cc/terms/second-cancers-after-radiotherapy/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-prevention-adoption/>, <https://onco.cc/bottlenecks/b-hereditary-risk/>, <https://onco.cc/bottlenecks/b-survivorship/> .