# OnCo record rejuv-trial-amico (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/rejuv-trial-amico/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "rejuv-trial-amico", "NCT04754672" ;
  schema:name "AMICO: aerobic or resistance exercise to improve outcome in metastatic colorectal cancer"@en ;
  schema:alternateName "AMICO"@en, "NCT04754672"@en ;
  schema:description "CHALLENGE showed exercise improves survival after curative treatment for colon cancer. AMICO asks the next question, in advanced disease, with chemotherapy dose modification and progression-free survival as its primary endpoints, and uses an adaptive design to drop an ineffective exercise prescription early."@en ;
  schema:url <https://onco.cc/trials/rejuv-trial-amico/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04754672>, <https://doi.org/10.1056/NEJMoa2502760> ;
  onco:status "recruiting" ;
  onco:tag "rejuvenation", "survivorship", "open-problem", "exercise", "trial-design" ;
  onco:phase "3" ;
  schema:startDate "2021-03-02" ;
  onco:related <https://onco.cc/trials/challenge/>, <https://onco.cc/technologies/exercise-prescription-after-cancer/>, <https://onco.cc/technologies/structured-exercise-survivorship/>, <https://onco.cc/technologies/exercise-oncology/>, <https://onco.cc/ideas/idea-rejuv-survivorship-platform-trial/>, <https://onco.cc/ideas/idea-nl-exercise-dose-finding/>, <https://onco.cc/roadmaps/rejuvenation-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> .