# OnCo record rejuv-tx-fertility-and-growth (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-tx-fertility-and-growth/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-tx-fertility-and-growth" ;
  schema:name "Fertility, growth and what total body irradiation costs"@en ;
  schema:alternateName "infertility after transplant"@en, "premature ovarian insufficiency after HSCT"@en, "growth after total body irradiation"@en, "TBI late effects"@en ;
  schema:description "Transplant conditioning, and total body irradiation in particular, usually ends natural fertility and in children slows growth. The decisions that preserve the most are made before conditioning starts. A randomised trial in children with leukaemia tested replacing the radiation with chemotherapy and found the radiation worked better."@en ;
  schema:url <https://onco.cc/technologies/rejuv-tx-fertility-and-growth/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Total_body_irradiation> ;
  schema:citation <https://doi.org/10.1007/s00277-025-06275-4>, <https://doi.org/10.3760/cma.j.cn121090-20250630-00307>, <https://doi.org/10.1016/j.jtct.2024.06.029>, <https://doi.org/10.1200/JCO.20.02529>, <https://doi.org/10.1016/j.bbmt.2011.12.519>, <https://doi.org/10.3324/haematol.2016.150250> ;
  onco:status "established" ;
  onco:tag "rejuvenation", "survivorship", "transplant", "fertility", "late-effects", "radiation" ;
  onco:related <https://onco.cc/technologies/rejuv-tx-endocrine-and-cardiometabolic/>, <https://onco.cc/technologies/rejuv-tx-late-effects-overview/>, <https://onco.cc/technologies/ovarian-function-after-chemotherapy/>, <https://onco.cc/technologies/menopause-after-cancer-treatment/>, <https://onco.cc/technologies/testosterone-after-cancer-treatment/>, <https://onco.cc/technologies/sexual-function-after-cancer/>, <https://onco.cc/technologies/rejuv-tx-quality-of-life/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/fertility-preservation/>, <https://onco.cc/technologies/total-body-irradiation/>, <https://onco.cc/technologies/allogeneic-hsct/>, <https://onco.cc/technologies/survivorship-care-plan/> ;
  onco:terms <https://onco.cc/terms/late-effects/>, <https://onco.cc/terms/conditioning-regimen/>, <https://onco.cc/terms/quality-of-life/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-survivorship/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> .