# OnCo record rejuv-tx-immune-reconstitution-timeline (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-tx-immune-reconstitution-timeline/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-tx-immune-reconstitution-timeline" ;
  schema:name "Rebuilding an immune system: the timeline, lineage by lineage"@en ;
  schema:alternateName "immune reconstitution after transplant"@en, "T cell recovery after HSCT"@en, "lymphocyte recovery after CAR-T"@en, "thymic function after transplant"@en ;
  schema:description "After a transplant the immune system comes back in a fixed order, and the order explains most of what follows. Neutrophils in two to four weeks, natural killer cells within a month, B cells over several months to a year, and T cells last and slowest. Adults rebuild a narrower repertoire, because the thymus shrinks with age."@en ;
  schema:url <https://onco.cc/technologies/rejuv-tx-immune-reconstitution-timeline/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Immune_reconstitution> ;
  schema:citation <https://doi.org/10.3389/fimmu.2016.00507>, <https://doi.org/10.1038/25374>, <https://doi.org/10.1016/j.bneo.2025.100090>, <https://doi.org/10.1016/j.bbmt.2009.06.019> ;
  onco:status "established" ;
  onco:tag "rejuvenation", "survivorship", "transplant", "immune", "reconstitution" ;
  onco:related <https://onco.cc/technologies/rejuv-frontier-immune-reconstitution/>, <https://onco.cc/technologies/rejuv-tx-b-cell-aplasia-and-immunoglobulin/>, <https://onco.cc/technologies/rejuv-tx-infection-by-phase/>, <https://onco.cc/technologies/rejuv-tx-revaccination/>, <https://onco.cc/technologies/gvhd-prophylaxis/>, <https://onco.cc/technologies/rejuv-tx-prolonged-cytopenias/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/allogeneic-hsct/>, <https://onco.cc/technologies/autologous-stem-cell-transplant/>, <https://onco.cc/technologies/car-t/> ;
  onco:terms <https://onco.cc/terms/late-effects/>, <https://onco.cc/terms/cytopenias/>, <https://onco.cc/terms/gvhd/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-survivorship/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> .