# OnCo record rejuv-tx-prolonged-cytopenias (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/rejuv-tx-prolonged-cytopenias/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "rejuv-tx-prolonged-cytopenias" ;
  schema:name "Blood counts that do not come back after CAR-T: ICAHT"@en ;
  schema:alternateName "ICAHT"@en, "immune effector cell-associated haematotoxicity"@en, "prolonged cytopenia after CAR-T"@en, "CAR-HEMATOTOX"@en ;
  schema:description "After CAR-T the blood counts often take much longer to recover than after ordinary chemotherapy, and in some people they dip again weeks later after appearing to have recovered. Since 2023 this has had a name, ICAHT, and an agreed grading system, which matters because it means it is measured and reported rather than described loosely."@en ;
  schema:url <https://onco.cc/technologies/rejuv-tx-prolonged-cytopenias/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Cytopenia> ;
  schema:citation <https://doi.org/10.1182/blood.2023020578>, <https://doi.org/10.1016/S2352-3026(24)00077-2>, <https://doi.org/10.1038/s41409-024-02278-3>, <https://doi.org/10.3324/haematol.2024.286027>, <https://doi.org/10.1182/blood-2017-07-793760> ;
  onco:status "established" ;
  onco:tag "rejuvenation", "survivorship", "transplant", "cell-therapy", "cytopenias" ;
  onco:related <https://onco.cc/technologies/rejuv-tx-immune-reconstitution-timeline/>, <https://onco.cc/technologies/rejuv-tx-infection-by-phase/>, <https://onco.cc/technologies/rejuv-tx-icans-and-neurocognition/>, <https://onco.cc/technologies/rejuv-tx-b-cell-aplasia-and-immunoglobulin/>, <https://onco.cc/technologies/rejuv-age-clonal-haematopoiesis-after-therapy/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/autologous-stem-cell-transplant/> ;
  onco:terms <https://onco.cc/terms/cytopenias/>, <https://onco.cc/terms/crs/>, <https://onco.cc/terms/late-effects/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-survivorship/> .