# OnCo record renal-medullary-carcinoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/renal-medullary-carcinoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "renal-medullary-carcinoma" ;
  schema:name "Renal medullary carcinoma (SMARCB1-deficient)"@en ;
  schema:alternateName "SMARCB1-deficient renal medullary carcinoma"@en, "Renal medullary carcinoma"@en, "RMC"@en, "Sickle cell nephropathy-associated carcinoma"@en ;
  schema:description "Renal medullary carcinoma is a very rare, very aggressive kidney cancer of young people who carry the sickle cell trait, driven by loss of the SMARCB1 gene. Most patients have spread at diagnosis and live about a year on average; chemotherapy and removal of the kidney are the main treatments, and better drugs are urgently needed."@en ;
  schema:url <https://onco.cc/cancers/renal-medullary-carcinoma/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Renal_medullary_carcinoma> ;
  schema:citation <https://www.cancer.gov/types/kidney/patient/kidney-treatment-pdq>, <https://doi.org/10.1016/j.eururo.2022.06.016>, <https://doi.org/10.1111/j.1365-2559.2012.04228.x>, <https://doi.org/10.1158/1078-0432.ccr-17-3296>, <https://doi.org/10.1111/bju.13705>, <https://doi.org/10.1097/pas.0b013e3182635954> ;
  onco:tag "subtype-page", "wave4", "kidney", "rare" ;
  onco:related <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/collecting-duct-carcinoma/>, <https://onco.cc/cancers/clear-cell-rcc/>, <https://onco.cc/cancers/papillary-rcc/> ;
  onco:targets <https://onco.cc/targets/smarcb1/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/gemcitabine/> ;
  onco:terms <https://onco.cc/terms/nephrectomy/> ;
  onco:standardOfCare <https://onco.cc/terms/nephrectomy/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/gemcitabine/> .