# OnCo record research-reactor-isotope-production (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/research-reactor-isotope-production/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "research-reactor-isotope-production" ;
  schema:name "Research reactors for medical isotopes (Mo-99, Lu-177, I-131)"@en ;
  schema:description "Most of the world's therapeutic and scanning isotopes are made by putting targets into about half a dozen ageing research reactors and flying the product out within days. When two reactors were down at once in 2009 and 2010, hospitals worldwide ran short of the most used scan isotope."@en ;
  schema:url <https://onco.cc/technologies/research-reactor-isotope-production/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://www.oecd-nea.org/jcms/pl_20168/medical-radioisotopes>, <https://www.isotopes.gov/>, <https://en.wikipedia.org/wiki/Technetium-99m#Shortages> ;
  onco:status "standard-of-care" ;
  onco:tag "manufacturing-wave" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/neuroendocrine/> ;
  onco:sections <https://onco.cc/fronts/radiopharma/> ;
  onco:technologies <https://onco.cc/technologies/therapy-isotope-supply-chain/>, <https://onco.cc/technologies/radionuclide-generators-kits/>, <https://onco.cc/technologies/cyclotron-isotope-production/>, <https://onco.cc/technologies/radiopharmaceutical-gmp-release/>, <https://onco.cc/technologies/radiopharmacy-network/>, <https://onco.cc/technologies/radioligand-therapy/>, <https://onco.cc/technologies/spect/> ;
  onco:drugs <https://onco.cc/drugs/pluvicto/>, <https://onco.cc/drugs/lutathera/>, <https://onco.cc/drugs/lu177-psma-it/> ;
  onco:companies <https://onco.cc/companies/curium/>, <https://onco.cc/companies/ire/>, <https://onco.cc/companies/ntp-radioisotopes/>, <https://onco.cc/companies/ansto/>, <https://onco.cc/companies/itm/>, <https://onco.cc/companies/isotopia/>, <https://onco.cc/companies/eckert-ziegler/>, <https://onco.cc/companies/bruce-power/>, <https://onco.cc/companies/nordion/>, <https://onco.cc/companies/shine-technologies/>, <https://onco.cc/companies/northstar-medical-radioisotopes/>, <https://onco.cc/companies/novartis/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/> .